Tealaprevir REALIZE trial

[banarep]

This was the trial I was in.   65% SVR

http://finance.yahoo.com/news/Vertexs-Telaprevir-zacks-2771078802.html?x=0&.v=1

[DougV]

Do you happen to remember the details?  Was this geno 1 only are all genotypes?  If 1's it's better then SOC but not as much as I would have like to have seen.  You were 24 weeks though, correct?

Doug

[banarep]

genotype 1 and 48 weeks.  I am trying to get ahold of my study doc and have him explain it all to me.  But 65% for retreaters is not bad.  What this does not show is how many of those 35% did not finish treatment, etc.   That is important to know.

In my study (3 of us) two got SVR and the other relapsed.

[banarep]

more results:

http://investors.vrtx.com/releasedetail.cfm?ReleaseID=505239

[greyrocker]

Thanks for this, BR. I'll include it in next month's newsletter.

GR

[DougV]

Forgotten you were a relapser, sorry 'bout that, which makes that 65% look on heck of a lot better.  With that rate I'd give it a shot, but 48 weeks?  I sure like 24 weeks much better. 

[banarep]

Doug,

Know what you mean.  But it does not seem to be in the cards for us.  That is why I have been telling those that do not need to treat to wait, not a doctor so I do not know why retreatment is still 48, but if you have never treated 24 often is enough.

I did 47, but what the heck, that is close to 48.